Having been a salesperson for years I learned early on that if people don't buy from me there is another person waiting for my call. I used to have a terrible time in sales and life success until I realised this point.
In my first weeks out of university, knowing that I wanted to be around people and liked the principle of selling, I managed to get myself an interview with an office equipment company. I passed this and ended up being out on the road with my company car and sample machines. I felt physically ill sometimes trying to book appointments and then trying to sell a machine once I was in the appointment. However, once I could separate the fear of rejection from the process of selling, life and my work became a lot simpler.
One of the reasons it became simpler, was that I realized that selling office products was not what I wanted to do, and I found other products and offerings I felt a better connection to. The other reason - and the one that was the most important in terms of feeling good about myself - is that I grasped the concept that it was a numbers game as well as being about relationships. By putting more effort into learning better skills with people, as well as stepping away from situations that were unprofessional, I began to enjoy the selling industry. I also started to get better results because I was focusing more on what the prospects wanted than on what I had done before, which was to make them want my product.
Often they were as keen to find someone to listen to them and to be able to hear the problems they were facing. If I had a solution for their issues, even better! Where there was simply no common ground between us, no mutual reason for being in contact with each other, then as soon as I let go of the need to feel liked or appreciated, the pain was gone. Either there was a working opportunity to do some thing or there was not, and no amount of being nice or wanting to be liked would make any difference at all.
This is true for life principles in that regardless of whether you are suggesting an opportunity, building a friendship, developing a network, or simply getting through your day, you are bound to be in contact with people you just cannot relate to. The fact that they feel the same is nothing to be concerned about.
Just find someone who either likes you and what you have to offer, or someone who just likes the offer because it is what they need and have been looking for. Either way you win. Both of you.